Provider records sourced from NPPES (CMS National Plan & Provider Enumeration System). Data current as of August 10, 2026.
NPIDirectory

Mathew Papakyrikos Mazzola, DO

Individual provider Internal Medicine Physician · NPI 1497275895

Mathew Papakyrikos Mazzola, DO practises Internal Medicine in Columbia, South Carolina. Qualified in 2017, 9 years ago. Practices with Lexington Health Inc, a 903-clinician group, accepts Medicare assignment and offers telehealth. Licensed in South Carolina.

Years since qualifying
9
Licensed in
SC
In the registry since
2017
What do these letters mean?
DO — Doctor of Osteopathic Medicine
A fully licensed physician, trained like an MD with additional musculoskeletal training. Equivalent practice rights in all 50 states.

See every abbreviation used in this directory →

Claim this listing Report a problem Suggest an edit

Practice location Address checks out

4540 Trenholm Rd
Columbia, SC 29206-4462
Phone: (803) 790-4700
Fax: (803) 790-6130
Show map & directions

Directions in Google Maps · Apple Maps · OpenStreetMap

Pin is approximate — placed at the ZIP-code centre, not the exact door.

Specialties & licences

Internal Medicine Physician (primary) Taxonomy 207R00000X · Licence LL40719 (SC)

Record details

NPI number1497275895
Entity typeIndividual (Type 1)
GenderMale
Credentials DO
Sole proprietorNo
NPI enumeratedJune 27, 2017
Last updated in NPPESNovember 9, 2020
Certification dateNovember 9, 2020

Medicare enrollment

From the CMS Doctors & Clinicians file — this clinician is enrolled in Medicare.

Medicare specialtyINTERNAL MEDICINE
Medical schoolOTHER
Graduated 2017 (9 years in practice)
Group practice Lexington Health Inc — 903 clinicians
Accepts Medicare assignment Yes — accepts the Medicare-approved amount
TelehealthOffers telehealth services

Medicare patients and services, 2024

From the CMS Medicare Physician & Other Practitioners file for calendar year 2024. It counts Original Medicare patients only, so a practice that mostly sees Medicare Advantage or privately insured patients looks smaller here than it is.

Medicare patients337
Services billed 4,608 a service is one billed item, such as a visit, a test or a procedure
Average patient age75

Dollar amounts are not shown. What Medicare pays a practice is gross billings, before staff, premises and tax and including the cost of any drugs it administers, so it is not what a clinician earns.

Payments from drug and device companies, 2025

Drug and device makers are required by federal law (the Physician Payments Sunshine Act) to report what they pay or give to clinicians, and CMS publishes the reports as Open Payments. This is the 2025 program year. A report is a record of a payment, not an allegation of anything, and many are small items such as meals. Only general payments are listed here; research payments and ownership or investment interests are reported separately by CMS and are not shown.

Food and Beverage $956 52 payments · a meal or drink at a meeting or visit, not a fee

Each amount is the sum of what companies reported for that kind of payment in 2025, rounded to the dollar. Not all of it is income to the clinician: a meal is not a fee, a charitable contribution goes to a charity, and a royalty or an acquisition payment is not a salary.

Check a report, or dispute one, at the source in CMS’s own tool, Open Payments. Corrections go through CMS’s dispute process. This site removes a home address on request and asks for no proof, because that is privacy; it will not remove an accurate payment report on request, because that is a statutory public disclosure.

Practises at

Facilities the CMS Facility Affiliation file lists for this clinician. Those with a page here are linked.

  • Lexington Medical Center Hospital · West Columbia, SC
  • Pruitthealth Home Health-Columbia Home health agency · Columbia, SC · listed as Pruitthealth Home Health, Inc
  • Prisma Health Baptist Hospital · Columbia, SC
  • Prisma Health Richland Hospital Hospital · Columbia, SC
  • Amedisys Home Health Of Camden Home health agency · Camden, SC

Colleagues at Lexington Health Inc

Clinicians the CMS Doctors & Clinicians file lists under the same group practice. CMS counts 903 clinicians in the practice; 12 are shown here.

Other providers in Columbia