Provider records sourced from NPPES (CMS National Plan & Provider Enumeration System). Data current as of August 10, 2026.
NPIDirectory

Mary Denise Hughes, MD

Individual provider Neurology Physician · NPI 1275643561

Mary Denise Hughes, MD practises Neurology in Greenville, South Carolina. Graduated from University of Tennessee, Hsc, College of Medicine in 1989, 37 years ago. Practices with Lifestyle Neurology LLC, a 4-clinician group, accepts Medicare assignment and offers telehealth. Licensed in Georgia and South Carolina.

Years since qualifying
37
Trained at
University of Tennessee, Hsc, College of Medicine
Licensed in
GA, SC
In the registry since
2006
Specialties on file
2
What do these letters mean?
MD — Doctor of Medicine
A physician who completed allopathic medical school.

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Practice location Address checks out

52 Bear Dr
Greenville, SC 29605-4458
Phone: (864) 655-4005
Fax: (864) 655-4004
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Pin is approximate — placed at the ZIP-code centre, not the exact door.

Specialties & licences

Neurology Physician (primary) Taxonomy 2084N0400X · Licence 30585 (SC)
Neurology Physician Taxonomy 2084N0400X · Licence 042614 (GA)

Record details

NPI number1275643561
Entity typeIndividual (Type 1)
GenderFemale
Credentials MD
Sole proprietorNo
NPI enumeratedAugust 30, 2006
Last updated in NPPESDecember 30, 2024
Certification dateDecember 30, 2024

Medicare enrollment

From the CMS Doctors & Clinicians file — this clinician is enrolled in Medicare.

Medicare specialtyNEUROLOGY
Medical schoolUNIVERSITY OF TENNESSEE, HSC, COLLEGE OF MEDICINE
Graduated 1989 (37 years in practice)
Group practice Lifestyle Neurology Llc — 4 clinicians
Accepts Medicare assignment Yes — accepts the Medicare-approved amount
TelehealthOffers telehealth services

Procedures

From CMS Care Compare, which counts the procedures a clinician billed to Original Medicare and Medicare Advantage over a recent 12-month period. CMS reports a fixed list of common procedures, so this is not everything the clinician does. Counts of 10 or fewer are given as a range, because CMS withholds small numbers.

Skin biopsy 1–10 times

The percentile compares how often this clinician performed the procedure with other clinicians who performed it, as CMS calculates it. It measures volume, not outcomes or skill.

Medicare patients and services, 2024

From the CMS Medicare Physician & Other Practitioners file for calendar year 2024. It counts Original Medicare patients only, so a practice that mostly sees Medicare Advantage or privately insured patients looks smaller here than it is.

Medicare patients260
Average patient age67

Dollar amounts are not shown. What Medicare pays a practice is gross billings, before staff, premises and tax and including the cost of any drugs it administers, so it is not what a clinician earns.

Payments from drug and device companies, 2025

Drug and device makers are required by federal law (the Physician Payments Sunshine Act) to report what they pay or give to clinicians, and CMS publishes the reports as Open Payments. This is the 2025 program year. A report is a record of a payment, not an allegation of anything, and many are small items such as meals. Only general payments are listed here; research payments and ownership or investment interests are reported separately by CMS and are not shown.

Compensation for services other than consulting , including serving as faculty or as a speaker at a venue other than a continuing education program $6,030 3 payments
Food and Beverage $3,041 122 payments · a meal or drink at a meeting or visit, not a fee
Consulting Fee $2,475 1 payment
Travel and Lodging $1,674 3 payments · travel or lodging paid or reimbursed, such as to attend a conference

Each amount is the sum of what companies reported for that kind of payment in 2025, rounded to the dollar. Not all of it is income to the clinician: a meal is not a fee, a charitable contribution goes to a charity, and a royalty or an acquisition payment is not a salary.

Check a report, or dispute one, at the source in CMS’s own tool, Open Payments. Corrections go through CMS’s dispute process. This site removes a home address on request and asks for no proof, because that is privacy; it will not remove an accurate payment report on request, because that is a statutory public disclosure.

Colleagues at Lifestyle Neurology LLC

Clinicians the CMS Doctors & Clinicians file lists under the same group practice.

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