Provider records sourced from NPPES (CMS National Plan & Provider Enumeration System). Data current as of August 10, 2026.
NPIDirectory

James C Charles, MD

Individual provider Infectious Disease Physician · NPI 1962405316

James C Charles, MD is registered under Infectious Disease in Rock Hill, South Carolina. Graduated from University of North Carolina at Chapel Hill School of Medicine in 1988, 38 years ago. Practices with Affinity Health Center, a 4-clinician group and accepts Medicare assignment. Licensed in South Carolina.

Years since qualifying
38
Trained at
University of North Carolina at Chapel Hill School of Medicine
Licensed in
SC
In the registry since
2005
Specialties on file
2
What do these letters mean?
MD — Doctor of Medicine
A physician who completed allopathic medical school.

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Practice location Address checks out

455 Lakeshore Pkwy
Rock Hill, SC 29730-4205
Phone: (803) 909-6363
Fax: (877) 658-8669
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Pin is approximate — placed at the ZIP-code centre, not the exact door.

Specialties & licences

Internal Medicine Physician (primary) Taxonomy 207R00000X · Licence 22318 (SC)
Infectious Disease Physician Taxonomy 207RI0200X · Licence 22318 (SC)

Record details

NPI number1962405316
Entity typeIndividual (Type 1)
GenderMale
Credentials MD
Sole proprietorYes
NPI enumeratedMay 31, 2005
Last updated in NPPESApril 28, 2026
Certification dateApril 28, 2026

Medicare enrollment

From the CMS Doctors & Clinicians file — this clinician is enrolled in Medicare.

Medicare specialtyINFECTIOUS DISEASE
Medical schoolUNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL SCHOOL OF MEDICINE
Graduated 1988 (38 years in practice)
Group practice Affinity Health Center — 4 clinicians
Accepts Medicare assignment Yes — accepts the Medicare-approved amount

Payments from drug and device companies, 2025

Drug and device makers are required by federal law (the Physician Payments Sunshine Act) to report what they pay or give to clinicians, and CMS publishes the reports as Open Payments. This is the 2025 program year. A report is a record of a payment, not an allegation of anything, and many are small items such as meals. Only general payments are listed here; research payments and ownership or investment interests are reported separately by CMS and are not shown.

Food and Beverage $1,055 59 payments · a meal or drink at a meeting or visit, not a fee

Each amount is the sum of what companies reported for that kind of payment in 2025, rounded to the dollar. Not all of it is income to the clinician: a meal is not a fee, a charitable contribution goes to a charity, and a royalty or an acquisition payment is not a salary.

Check a report, or dispute one, at the source in CMS’s own tool, Open Payments. Corrections go through CMS’s dispute process. This site removes a home address on request and asks for no proof, because that is privacy; it will not remove an accurate payment report on request, because that is a statutory public disclosure.

Colleagues at Affinity Health Center

Clinicians the CMS Doctors & Clinicians file lists under the same group practice. CMS counts 4 clinicians in the practice; 2 are shown here.

Other providers in Rock Hill